The association of Cytochrome 4F2 rs2108622 genetic variant and non-genetic factors with essential hypertension among Jordanian patients attending the University of Jordan Hospital.

doi:10.1016/j.prostaglandins.2025.107045

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The association of Cytochrome 4F2 rs2108622 genetic variant and non-genetic factors with essential hypertension among Jordanian patients attending the University of Jordan Hospital.

Prostaglandins & other lipid mediators - 1 Dec 2025

Alkasasbeh Enas Yousef, Jarrar Yazun Bashir, Khalil Wiam, Alhawari Hussein, Zihlif Malek

Abstract excerpt

BACKGROUND: Essential hypertension (EH) contributes to death and morbidity. CYP4 genes influence EH via 20-hydroxyeicosatetraenoic acid production. Identifying genetic risk factors may reveal biomarkers for EH among Jordanian patients. AIM: To determine the prevalence of CYP4F2 rs2108622 genetic variants, determine their influence on the systolic (SBP) and diastolic blood pressure (DBP), and their association...

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PMID: 41274339
DOI: 10.1016/j.prostaglandins.2025.107045

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CYP4F2
DBP

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