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Article

Functional polymorphism in human CYP4F2 decreases 20-HETE production.

Physiological genomics - 19 Jun 2007

Stec David E, Roman Richard J, Flasch Averia, Rieder Mark J

Abstract excerpt

20-Hydroxyeicosatetraenoic acid (20-HETE) plays an important role in the regulation of renal tubular and vascular function and a deficiency in the renal formation of 20-HETE has been linked to the development of hypertension. The cytochrome P450 4F2 (CYP4F2) gene encodes for the major CYP enzyme responsible for the synthesis of 20-HETE in the human kidney. We screened two human sampling panels (African and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17341693
DOI: 10.1152/physiolgenomics.00003.2007

Genes

LTB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional polymorphism in human CYP4F2 decreases 20-HETE production.PMID 17341693Read ↗

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