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An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium

15 Jun 2021

Abstract excerpt

Significance Clostridioides difficile is the leading cause of healthcare-associated diarrhea worldwide following antibiotic treatment. Consequently, there is medical need for novel antibacterial agents acting against C. difficile that leave the resident microbiota unharmed. The development of such narrow-spectrum antibiotics requires precise knowledge of the mechanisms that fine-tune gene expression to...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 34131082
DOI: 10.1073/pnas.2103579118

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