Article
Clostridium difficile Hfq can replace Escherichia coli Hfq for most of its function.
RNA (New York, N.Y.) - 1 Oct 2014
Caillet Joel, Gracia Céline, Fontaine Fanette, Hajnsdorf Eliane
Abstract excerpt
A gene for the Hfq protein is present in the majority of sequenced bacterial genomes. Its characteristic hexameric ring-like core structure is formed by the highly conserved N-terminal regions. In contrast, the C-terminal forms an extension, which varies in length, lacks homology, and is predicted to be unstructured. In Gram-negative bacteria, Hfq facilitates the pairing of sRNAs with their mRNA target and thus...
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