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An RNA-centric global view of <i>Clostridioides difficile</i> reveals broad activity of Hfq in a clinically important Gram-positive bacterium

2020-08-10

Abstract excerpt

<h4>ABSTRACT</h4> The Gram-positive human pathogen Clostridioides difficile has emerged as the leading cause of antibiotic-associated diarrhea. Despite growing evidence for a role of Hfq in RNA-based gene regulation in C. difficile , little is known about the bacterium’s transcriptome architecture and mechanisms of post-transcriptional control. Here, we have applied a suite of RNA-centric techniques, including...

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Literature Corpus work
0bc751ed-4b90-55b1-95ec-fbb01b8531d5
DOI
10.1101/2020.08.10.244764
Open publication

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An RNA-centric global view of <i>Clostridioides difficile</i> reveals broad activity of Hfq in a clinically important Gram-positive bacteriumDOI 10.1101/2020.08.10.244764
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