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Article

Transcription factors modulate c-Fos transcriptional bursts.

Cell reports - 10 Jul 2014

Senecal Adrien, Munsky Brian, Proux Florence, Ly Nathalie, Braye Floriane E, Zimmer Christophe, Mueller Florian, Darzacq Xavier

Abstract excerpt

Transcription is a stochastic process occurring mostly in episodic bursts. Although the local chromatin environment is known to influence the bursting behavior on long timescales, the impact of transcription factors (TFs)--especially in rapidly inducible systems--is largely unknown. Using fluorescence in situ hybridization and computational models, we quantified the transcriptional activity of the proto-oncogene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24981864
DOI: 10.1016/j.celrep.2014.05.053
PMCID: PMC5555219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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