Article

Multiplexed, scalable analog recording of gene regulation dynamics over weeks using intracellular protein tapes

2025-05-10

Abstract excerpt

Gene expression is constantly regulated by gene regulatory networks that consist of multiple regulatory components to mediate cellular functions. An ideal tool for analyzing gene regulation processes would provide simultaneous measurements of the dynamics of many components in the gene regulatory network, but existing methodologies fall short of simultaneously tracking the dynamics of components over long periods...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56b5726a-196b-5487-ab31-180319dbf353
DOI: 10.1101/2025.05.10.653182

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiplexed, scalable analog recording of gene regulation dynamics over weeks using intracellular protein tapesDOI 10.1101/2025.05.10.653182Read

Fluorescent protein-based ticker tapes for multiplexed recordings of transcriptional histories in single cells in culture and in vivoSemantic proximity Read

Recording of cellular physiological histories along optically readable self-assembling protein chainsSemantic proximity Read

Simultaneous brain-wide single-cell recording resolves spatiotemporal memory architectureSemantic proximity Read

Molecular recording of cellular protein kinase activity with chemical labelingSemantic proximity Read

Single-cell FM streaming using genetically encoded protein oscillatorsSemantic proximity Read

Single-Cell Trajectory Inference for Detecting Transient Events in Biological ProcessesSemantic proximity Read

Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosuresSemantic proximity Read

Reconstructing signaling history of single cells with imaging-based molecular recordingSemantic proximity Read

Genomic repeats for single-cell molecular recordingSemantic proximity Read

Identification of molecular determinants of gene-specific bursting patterns by high-throughput imaging screensSemantic proximity Read

Simultaneous single cell measurements of intranuclear proteins and gene expressionSemantic proximity Read

Live-seq enables temporal transcriptomic recording of single cells.Semantic proximity Read