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Article

DNA methylation accumulation and its predetermination of future cancer phenotypes.

Journal of biochemistry - 1 Aug 2014

Kaneda Atsushi, Matsusaka Keisuke, Sakai Eiji, Funata Sayaka

Abstract excerpt

Aberant DNA methylation is a common epigenomic alteration in carcinogenesis. Comprehensive analyses of DNA methylation have stratified gastrointestinal cancer into several subgroups according to specific DNA methylation accumulation. In gastric cancer, Helicobacter pylori infection is a cause of methylation accumulation in apparently normal mucosa. Epstein-Barr virus infection is another methylation inducer that...

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Identifiers

PMID: 24962701
DOI: 10.1093/jb/mvu038

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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