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Article

Epigenetic impact of infection on carcinogenesis: mechanisms and applications

28 Jan 2016

Abstract excerpt

Viral and bacterial infections are involved in the development of human cancers, such as liver, nasopharyngeal, cervical, head and neck, and gastric cancers. Aberrant DNA methylation is frequently present in these cancers, and some of the aberrantly methylated genes are causally involved in cancer development and progression. Notably, aberrant DNA methylation can be present even in non-cancerous or precancerous...

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PMID: 26823082
DOI: 10.1186/s13073-016-0267-2

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