Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

doi:10.1016/j.drugalcdep.2014.05.023

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Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.

Drug and alcohol dependence - 1 Sept 2014

Kapoor Manav, Wang Jen-Chyong, Wetherill Leah, Le Nhung, Bertelsen Sarah, Hinrichs Anthony L, Budde John, Agrawal Arpana, Almasy Laura, Bucholz Kathleen, Dick Danielle M, Harari Oscar, Xiaoling Xuei, Hesselbrock Victor, Kramer John, Nurnberger John I, Rice John, Schuckit Marc, Tischfield Jay, Porjesz Bernice, Edenberg Howard J, Bierut Laura, Foroud Tatiana, Goate Alison

Abstract excerpt

BACKGROUND: The age at onset of alcohol dependence (AD) is a critical moderator of genetic associations for alcohol dependence. The present study evaluated whether single nucleotide polymorphisms (SNPs) can influence the age at onset of AD in large high-risk families from the Collaborative Study on the Genetics of Alcoholism (COGA). METHODS: Genomewide SNP genotyping was performed in 1788 regular drinkers from...

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PMID: 24962325
DOI: 10.1016/j.drugalcdep.2014.05.023
PMCID: PMC4127128

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UTP20
ARL15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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