Article
Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2011
Wang Ke-Sheng, Liu Xuefeng, Aragam Nagesh, Jian Xueqiu, Mullersman Jerald E, Liu Yali, Pan Yue
Abstract excerpt
Family, twin, and adoption studies have indicated that genetic and environmental factors contribute to the development of alcohol dependence (AD). We conducted a low-density genome-wide association analysis to identify genetic variants influencing AD. We used 11,120 SNPs from the Affymetrix 10K Genechips genotyped in 116 Caucasian pedigrees (272 nuclear families) from Genetic Analysis Workshop 14, a subset from...
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