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Article

Variant RH alleles and Rh immunisation in patients with sickle cell disease.

Blood transfusion = Trasfusione del sangue - 1 Jan 2015

Sippert Emilia, Fujita Claudia R, Machado Debora, Guelsin Glaucia, Gaspardi Ane C, Pellegrino Jordão, Gilli Simone, Saad Sara S T O, Castilho Lilian

Abstract excerpt

BACKGROUND: Alloimmunisation is a major complication in patients with sickle cell disease (SCD) receiving red blood cell (RBC) transfusions and despite provision of Rh phenotyped RBC units, Rh antibodies still occur. These antibodies in patients positive for the corresponding Rh antigen are considered autoantibodies in many cases but variant RH alleles found in SCD patients can also contribute to Rh...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24960646
DOI: 10.2450/2014.0324-13
PMCID: PMC4317093

Genes

SCD
RHCE
RHD

Provenance

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