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Article

RH genotypes and red cell alloimmunization rates in chronically transfused patients with sickle cell disease: A multisite study in the USA.

Transfusion - 1 Mar 2024

Israelyan Narek, Vege Sunitha, Friedman David F, Zhang Zhe, Uter Stacey, Fasano Ross M, Yee Marianne, Piccone Connie, Kelly Shannon, Hankins Jane S, Zheng Yan, Westhoff Connie M, Chou Stella T

Abstract excerpt

BACKGROUND: Red cell alloimmunization remains a challenge for individuals with sickle cell disease (SCD) and contributes to increased risk of hemolytic transfusion reactions and associated comorbidities. Despite prophylactic serological matching for ABO, Rh, and K, red cell alloimmunization persists, in part, due to a high frequency of variant RH alleles in patients with SCD and Black blood donors. STUDY DESIGN...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38289184
DOI: 10.1111/trf.17740
PMCID: PMC10947898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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