Article
Red blood cell minor antigen mismatches during chronic transfusion therapy for sickle cell anemia.
Transfusion - 1 Nov 2017
Yee Marianne E M, Josephson Cassandra D, Winkler Anne M, Webb Jennifer, Luban Naomi L C, Leong Traci, Stowell Sean R, Fasano Ross M
Abstract excerpt
BACKGROUND: Red blood cell (RBC) alloimmunization occurs at a high frequency in sickle cell anemia (SCA) despite serologic matching for Rh (C/c, E/e) and K antigens. RBC minor antigen genotyping allows for prediction of antigens and RH variants that may lead to alloimmunization. STUDY DESIGN AND METHODS: RBC antigen genotyping was performed on chronically transfused pediatric SCA patients, using PreciseType human...
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