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RHCE and Kell genotyping and alloimmunization profile in patients with sickle cell disease in the Federal District of Brazil

15 Jun 2023

Abstract excerpt

INTRODUCTION: Sickle cell disease (SCD) is the most important hemoglobinopathy worldwide. The treatment often requires phenotype-matched red blood cell (RBC) transfusions, but alloimmunization to non-ABO antigens may occur in a part of the SCD patients. The genotyping has been used for RBC antigen prediction, reducing the possibility of the alloimmunization. OBJECTIVE AND METHOD: In this study we performed the...

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PMID: 37344342
DOI: 10.1016/j.htct.2023.05.004

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