Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of novel RHD alleles: relationship between phenotype, genotype, and trimeric architecture.

Transfusion - 1 Sept 2012

Silvy Monique, Chapel-Fernandes Sylvie, Callebaut Isabelle, Beley Sophie, Durousseau Cécile, Simon Sophie, Lauroua Pierre, Dubosc-Marchenay Nadine, Babault Catherine, Mouchet Chantal, Ferrera Virginie, Chiaroni Jacques, Bailly Pascal

Abstract excerpt

BACKGROUND: RH1 is one of the most clinically important blood group antigens in the field of transfusion and prevention of fetomaternal incompatibilities. New variant RHD alleles are regularly identified and their characterization is essential to ensuring patient safety. STUDY DESIGN AND METHODS: Blood samples with uncertain RhD phenotypes not resolved by our first-line SNaPshot assay were sequenced for all 10...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protein Multimerization
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitope Mapping

Share to Mutant Proteins

Share to Protein Structure, Quaternary

Share to Rh-Hr Blood-Group System

Share to Sequence Homology, Amino Acid

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 22320258
DOI: 10.1111/j.1537-2995.2011.03544.x

Genes

RHD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of novel RHD alleles: relationship between phenotype, genotype, and trimeric architecture.PMID 22320258Read ↗

Genetic diversity of the RHD gene in blood donors from the Brazilian Central-WestSemantic proximity Read ↗

The Significance of RHD Genotyping and Characteristic Analysis in Chinese RhD Variant Individuals.Semantic proximity Read ↗

From genetic variability to phenotypic expression of blood group systems.Semantic proximity Read ↗

A D+ blood donor with a novel RHD*D-CE(5-6)-D gene variant exhibits the low-frequency antigen RH23 (D(W) ) characteristic of the partial DVa phenotype.Semantic proximity Read ↗

RHCE variants inherited with altered RHD alleles in Brazilian blood donors.Semantic proximity Read ↗

Transfusion support for a woman with RHD*09.01.02 and the novel RHD*01W.161 allele in trans.Semantic proximity Read ↗

The RHD(1227G>A) DEL-associated allele is the most prevalent DEL allele in Australian D- blood donors with C+ and/or E+ phenotypes.Semantic proximity Read ↗

Novel intronic RHD variants identified in serologically D-negative blood donors.Semantic proximity Read ↗

Complete RHD next-generation sequencing: establishment of reference RHD allelesSemantic proximity Read ↗

RHD alleles in Brazilian blood donors with weak D or D-negative phenotypes.Semantic proximity Read ↗

New RHCE variant alleles encoding the D- - phenotype.Semantic proximity Read ↗

A Novel RHCE*cE (c.827C>A) Allele, Containing the Single-Nucleotide Change, Encodes Altered c/E Antigens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.