Article
Relevance of RH variants in transfusion of sickle cell patients.
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Dec 2011
Noizat-Pirenne F, Tournamille C
Abstract excerpt
Transfusion remains the main treatment of sickle cell disease patients. Red cell alloimmunization is frequent because of the antigen disparities between patients of African descent and donors of European ancestry. Alloimmunization is associated with severe hemolytic transfusion reaction, autoantibody formation, and difficulties in the management of transfusion compatibility. Beside common antigens, a number of...
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