Article
Impact of Red Blood Cell Antigen Matching on Alloimmunization and Transfusion Complications in Patients with Sickle Cell Disease: A Systematic Review.
Transfusion medicine reviews - 1 Jan 2019
Fasano Ross M, Meyer Erin K, Branscomb Jane, White Mia S, Gibson Robert W, Eckman James R
Abstract excerpt
Red blood cells (RBC) transfusion is critical in managing acute and chronic complications in sickle cell disease (SCD); however, it is complicated by RBC alloimmunization, iron overload, transfusion reactions and infection. Several reports documented an increased incidence of alloantibodies in transfused individuals with SCD, especially for Rh and Kell antigens. As a result, the National Institutes of Health...
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