Article
The (G>A) rs11573191 polymorphism of PLA2G5 gene is associated with premature coronary artery disease in the Mexican Mestizo population: the genetics of atherosclerotic disease Mexican study.
BioMed research international - 1 Jan 2014
Vargas-Alarcón Gilberto, Posadas-Romero Carlos, Villarreal-Molina Teresa, Alvarez-León Edith, Angeles-Martinez Javier, Soto María Elena, Monroy-Muñoz Irma, Juárez Juan Gabriel, Sánchez-Ramírez Carlos Jerges, Ramirez-Bello Julian, Ramírez-Fuentes Silvestre, Fragoso José Manuel, Rodríguez-Pérez José Manuel
Abstract excerpt
Coronary artery disease (CAD) is a multifactorial disorder that results from an excessive inflammatory response. Secretory phospholipase A2-V (sPLA2-V) encoded by PLA2G5 gene promotes diverse proinflammatory processes. The aim of the present study was to analyze if PLA2G5 gene polymorphisms are associated with premature CAD. Three PLA2G5 polymorphisms (rs11573187, rs2148911, and rs11573191) were analyzed in 707...
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