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Genetic Basis of Atherosclerosis: The Role of PLAU Gene Polymorphism in Coronary Artery Disease.

Genetic testing and molecular biomarkers - 1 Jun 2026

Bora Rıdvan, Tanrıverdi Rojda, Balcı Şenay, Gülüm Cemil, Aytimur Selman, Keçeci Ahmet Burak, Döven Oben, Tamer Lülüfer, Toprak Burak

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) is a multifactorial disorder influenced by both environmental and genetic factors. The PLAU gene, which plays a key role in fibrinolysis, inflammation, and extracellular matrix remodeling, has been implicated in atherosclerotic plaque progression. However, the relationship between PLAU polymorphisms and different clinical manifestations of CAD remains insufficiently...

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Identifiers

PMID: 42059534
DOI: 10.1177/19450265261447209

Genes

PLAU
CAD
CCS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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