Article
IL-24 gene polymorphisms are associated with cardiometabolic parameters and cardiovascular risk factors but not with premature coronary artery disease: the genetics of atherosclerotic disease Mexican study.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Sept 2014
Vargas-Alarcón Gilberto, Posadas-Romero Carlos, Villarreal-Molina Teresa, Alvarez-León Edith, Angeles-Martinez Javier, Posadas-Sanchez Rosalinda, Monroy-Muñoz Irma, Luna-Fuentes Sergio, González-Salazar Carmen, Ramirez-Bello Julian, Cardoso-Saldaña Guillermo, Medina-Urrutia Aida, Kimura-Hayama Eric
Abstract excerpt
Coronary artery disease (CAD) is a multifactorial and polygenic disorder that results from an excessive inflammatory response. We analyzed whether interleukin-24 (IL-24) gene polymorphisms are associated with premature CAD in a case-control association study. Four polymorphisms (rs1150253, rs1150256, rs1150258, and rs3762344) of the IL-24 gene were analyzed by 5' exonuclease TaqMan genotyping assays in a group of...