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Article

Molecular and functional characterization of polymorphisms in the secreted phospholipase A2 group X gene: relevance to coronary artery disease.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2009

Gora Sarah, Perret Claire, Jemel Ikram, Nicaud Viviane, Lambeau Gérard, Cambien François, Ninio Ewa, Blankenberg Stefan, Tiret Laurence, Karabina Sonia-Athina

Abstract excerpt

Among secreted phospholipases A2 (sPLA2s), human group X sPLA2 (hGX sPLA2) is emerging as a novel attractive therapeutic target due to its implication in inflammatory diseases. To elucidate whether hGX sPLA2 plays a causative role in coronary artery disease (CAD), we screened the human PLA2G10 gene to identify polymorphisms and possible associations with CAD end-points in a prospective study, AtheroGene. We...

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Identifiers

PMID: 19495570
DOI: 10.1007/s00109-009-0483-y
PMCID: PMC2700867

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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