Article
Monocyte chemoattractant protein-1 gene (MCP-1) polymorphisms are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.
Immunology letters - 1 Oct 2015
Angeles-Martínez Javier, Posadas-Sánchez Rosalinda, Álvarez-León Edith, Villarreal-Molina Teresa, Cardoso-Saldaña Guillermo, Fragoso José Manuel, Juárez-Rojas Juan Gabriel, Medina-Urrutia Aida, Posadas-Romero Carlos, Vargas-Alarcón Gilberto
Abstract excerpt
The CC chemokine monocyte chemoattractant protein (MCP)-1/CCL2 is involved in the formation, progression, and destabilization of atheromatous plaques and plays an essential role in postinfarction remodeling. The aim of the present study was to evaluate the role of MCP-1 gene polymorphisms as susceptibility markers for premature coronary artery disease (CAD) and cardiovascular risk factors in the Mexican...
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