Article
PHACTR1 Gene Polymorphism Is Associated with Increased Risk of Developing Premature Coronary Artery Disease in Mexican Population.
International journal of environmental research and public health - 9 Aug 2016
Pérez-Hernández Nonanzit, Vargas-Alarcón Gilberto, Posadas-Sánchez Rosalinda, Martínez-Rodríguez Nancy, Tovilla-Zárate Carlos Alfonso, Rodríguez-Cortés Adrián Asael, Pérez-Méndez Oscar, Blachman-Braun Ruben, Rodríguez-Pérez José Manuel
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in the protein phosphatase and actin regulator 1 gene (PHACTR1) have been associated with susceptibility to develop several diseases, including cardiovascular disease. The purpose of this study was to evaluate the role of two polymorphisms (rs2026458 and rs9349379) of the PHACTR1 gene in the susceptibility to the risk of developing premature coronary artery disease (CAD) in...
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