Article
Transcriptional response to vancomycin in a highly vancomycin-resistant Streptomyces coelicolor mutant.
Future microbiology - 1 Jan 2014
Santos-Beneit Fernando, Fernández-Martínez Lorena T, Rodríguez-García Antonio, Rodríguez García Antonio, Martín-Martín Seomara, Ordóñez-Robles María, Yagüe Paula, Manteca Angel, Martín Juan F
Abstract excerpt
AIM: The main objective of this study is to understand the mechanism of vancomycin resistance in a Streptomyces coelicolor disrupted mutant highly resistant to vancomycin. MATERIALS & METHODS: Different techniques have been performed in the study including gene disruption, primer extension, antibiotic susceptibility tests, electron microscopy, confocal microscopy, cell wall analysis and microarrays. RESULTS:...
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