Article
Mechanisms of vancomycin resistance in Staphylococcus aureus.
The Journal of clinical investigation - 1 Jul 2014
Gardete Susana, Tomasz Alexander
Abstract excerpt
Vancomycin is a glycopeptide antibiotic used for the treatment of Gram-positive bacterial infections. Traditionally, it has been used as a drug of last resort; however, clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) strains with decreased susceptibility to vancomycin (vancomycin intermediate-resistant S. aureus [VISA]) and more recently with high-level vancomycin resistance...
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