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Article

Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses' Health Study.

PloS one - 1 Jan 2019

Kim Iris Y, Grodstein Francine, Kraft Peter, Curhan Gary C, Hughes Katherine C, Huang Hongyan, Kang Jae H, Hunter David J

Abstract excerpt

OBJECTIVE: To examine the interaction between APOE genotypes and both treated and untreated hypertension on cognitive function in an updated analysis of Nurses' Health Study (NHS) data. DESIGN: At baseline (1995-2001) and 3 biennial follow-up assessments over ~6 years, cognitive function was assessed. SETTING AND PARTICIPANTS: 8300 NHS participants aged 70+ years underwent a cognitive battery, which comprised 6...

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Identifiers

PMID: 31697783
DOI: 10.1371/journal.pone.0224975
PMCID: PMC6837309

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