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Article

Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 May 2009

Knopman David S, Mosley Thomas H, Catellier Diane J, Coker Laura H

Abstract excerpt

BACKGROUND: Strokes, vascular risk factors, and apolipoprotein E (APOE) genotype are associated with cognitive decline in the elderly, but definitive evidence that these affect cognition as early as middle age is limited. OBJECTIVE: We describe the relationships of APOE genotype, stroke, and vascular risk factors with cognitive change over a 14-year follow-up in the Atherosclerosis Risk in Communities (ARIC)...

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Identifiers

PMID: 19362884
DOI: 10.1016/j.jalz.2009.01.027

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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