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Article

IRS1 G972R missense polymorphism is associated with failure to oral antidiabetes drugs in white patients with type 2 diabetes from Italy.

Diabetes - 1 Sept 2014

Prudente Sabrina, Morini Eleonora, Lucchesi Daniela, Lamacchia Olga, Bailetti Diego, Mercuri Luana, Alberico Federica, Copetti Massimiliano, Pucci Laura, Fariello Stefania, Giusti Laura, Cignarelli Mauro, Penno Giuseppe, De Cosmo Salvatore, Trischitta Vincenzo

Abstract excerpt

This study tried to replicate in a large sample of white patients with type 2 diabetes (T2D) from Italy a previously reported association of the IRS1 G972R polymorphism with failure to oral antidiabetes drugs (OAD). A total of 2,409 patients from four independent studies were investigated. Case s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24947357
DOI: 10.2337/db13-1966

Genes

IRS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24947357-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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IRS1 G972R missense polymorphism is associated with failure to oral antidiabetes drugs in white patients with type 2 diabetes from Italy.PMID 24947357Read ↗

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