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Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: a candidate gene study.

Metabolism: clinical and experimental - 1 Jan 2010

Burguete-Garcia Ana I, Cruz-Lopez Miguel, Madrid-Marina Vicente, Lopez-Ridaura Ruy, Hernández-Avila Mauricio, Cortina Bernardo, Gómez Rosa E, Velasco-Mondragón Eduardo

Abstract excerpt

Type 2 diabetes mellitus (T2D) is a main public health problem in the Mexican population. It is characterized by insulin resistance in peripheral tissues and a relative deficiency in the pancreatic beta-cell functions. Diverse single nucleotide polymorphisms (SNPs) of the IRS1 gene have been associated with insulin resistance and T2D risk. The aim of this study was to identify the association between known IRS1...

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Identifiers

PMID: 19716569
DOI: 10.1016/j.metabol.2009.07.007

Genes

IRS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: a candidate gene study.PMID 19716569Read ↗

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DNA polymorphism analysis of candidate genes for type 2 diabetes mellitus in a Mexican ethnic group.Semantic proximity Read ↗

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.Semantic proximity Read ↗

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