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Article

Transmission selects for HIV-1 strains of intermediate virulence: a modelling approach.

PLoS computational biology - 1 Oct 2011

Shirreff George, Pellis Lorenzo, Laeyendecker Oliver, Fraser Christophe

Abstract excerpt

Recent data shows that HIV-1 is characterised by variation in viral virulence factors that is heritable between infections, which suggests that viral virulence can be naturally selected at the population level. A trade-off between transmissibility and duration of infection appears to favour virus...

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Identifiers

PMID: 22022243
DOI: 10.1371/journal.pcbi.1002185
PMCID: PMC3192807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22022243-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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