Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of contact structure on the transient evolution of HIV virulence.

PLoS computational biology - 1 Mar 2017

Park Sang Woo, Bolker Benjamin M

Abstract excerpt

Early in an epidemic, high densities of susceptible hosts select for relatively high parasite virulence; later in the epidemic, lower susceptible densities select for lower virulence. Thus over the course of a typical epidemic the average virulence of parasite strains increases initially, peaks partway through the epidemic, then declines again. However, precise quantitative outcomes, such as the peak virulence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Epidemics
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Host-Pathogen Interactions

Share to Sexual Behavior

Share to Viral Load

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 28362805
DOI: 10.1371/journal.pcbi.1005453
PMCID: PMC5391972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of contact structure on the transient evolution of HIV virulence.PMID 28362805Read ↗

Transmission selects for HIV-1 strains of intermediate virulence: a modelling approach.Semantic proximity Read ↗

An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral LoadSemantic proximity Read ↗

Evolution of HIV virulence in response to widespread scale up of antiretroviral therapy: a modeling studySemantic proximity Read ↗

A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in UgandaSemantic proximity Read ↗

IS HIV SHORT‐SIGHTED? INSIGHTS FROM A MULTISTRAIN NESTED MODELSemantic proximity Read ↗

Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context.Semantic proximity Read ↗

Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T Cell Decline and Per-Parasite PathogenicitySemantic proximity Read ↗

Transient virulence of emerging pathogens.Semantic proximity Read ↗

Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity.Semantic proximity Read ↗

THE EVOLUTION OF VIRULENCE IN PATHOGENS WITH VERTICAL AND HORIZONTAL TRANSMISSIONSemantic proximity Read ↗

Acute or Chronic? Within‐Host Models with Immune Dynamics, Infection Outcome, and Parasite EvolutionSemantic proximity Read ↗

EVOLUTION OF VIRULENCE IN HETEROGENEOUS HOST COMMUNITIES UNDER MULTIPLE TRADE-OFFSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.