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Article

Single-nucleotide polymorphisms in the PLA2R1 gene are associated with systemic lupus erythematosus and lupus nephritis in a Chinese Han population.

Immunologic research - 1 Feb 2016

Li Yuan, Zhou Aihong, Lv Guanting, Li Ping, Chen Si, Li Jing, Wen Xiaoting, Wu Ziyan, Zhang Shulan, Wang Jibo, Zhang Fengchun, Li Yongzhe

Abstract excerpt

Several novel susceptibility genes for systemic lupus erythematosus (SLE) and other nephropathy have been identified in recent genome-wide association studies. Membranous nephropathy is the most common diagnosis in adults with the nephrotic syndrome, and both idiopathic membranous nephropathy (IMN) and lupus nephritis (LN) are autoimmune diseases of the kidney; they may share common disease mechanisms that...

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PMID: 26645973
DOI: 10.1007/s12026-015-8755-9

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