Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severe radiotoxicity in an allogeneic transplant recipient with a heterozygous ATM mutation.

European journal of haematology - 1 Jul 2015

Ostendorf Benjamin N, Terwey Theis H, Hemmati Philipp G, Böhmer Dirk, Pleyer Uwe, Arnold Renate

Abstract excerpt

Patients receiving radiotherapy often experience toxicity of the skin and mucous membranes. While radiotherapy is a mainstay of myeloablative conditioning for allogeneic hematopoietic stem cell transplantation (ASCT), no risk factors for radiotoxicity have been identified in this setting. Here, we report on a patient with excessive radiation-induced toxicity after ASCT who carried a heterozygous mutation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to B-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Remission Induction

Share to Transplantation Conditioning

Share to Transplantation, Homologous

Share to Whole-Body Irradiation

Source

Identifiers

PMID: 24935205
DOI: 10.1111/ejh.12400

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severe radiotoxicity in an allogeneic transplant recipient with a heterozygous ATM mutation.PMID 24935205Read ↗

Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer.Semantic proximity Read ↗

Functional consequences of ATM sequence variants for chromosomal radiosensitivity.Semantic proximity Read ↗

[Adjuvant irradiation in breast cancer patients with ATM gene heterozygous mutations: special focus on clinical efficacy/toxicity].Semantic proximity Read ↗

Enhanced radiation late effects and cellular radiation sensitivity in an ATM heterozygous breast cancer patient.Semantic proximity Read ↗

Human fibroblasts transfected with an ATM antisense vector respond abnormally to ionizing radiation.Semantic proximity Read ↗

High incidence of cancer in a family segregating a mutation of the ATM gene: possible role of ATM heterozygosity in cancer.Semantic proximity Read ↗

Atm heterozygosity does not increase tumor susceptibility to ionizing radiation alone or in a p53 heterozygous background.Semantic proximity Read ↗

Modest increased sensitivity to radiation oncogenesis in ATM heterozygous versus wild-type mammalian cells.Semantic proximity Read ↗

ATM polymorphisms are associated with risk of radiation-induced pneumonitis.Semantic proximity Read ↗

Cellular responses to radiation and risk of breast cancer.Semantic proximity Read ↗

Atm haploinsufficiency does not affect ionizing radiation mutagenesis in solid mouse tissues.Semantic proximity Read ↗

ATM gene single nucleotide polymorphisms predict regimen-related gastrointestinal toxicity in patients allografted after reduced conditioning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.