Article
ATM polymorphisms are associated with risk of radiation-induced pneumonitis.
International journal of radiation oncology, biology, physics - 1 Aug 2010
Zhang Li, Yang Ming, Bi Nan, Fang Mingjing, Sun Tong, Ji Wei, Tan Wen, Zhao Lujun, Yu Dianke, Lin Dongxin, Wang Luhua
Abstract excerpt
PURPOSE: Since the ataxia telangiectasia mutated (ATM) protein plays crucial roles in repair of double-stranded DNA breaks, control of cell cycle checkpoints, and radiosensitivity, we hypothesized that variations in this gene might be associated with radiation-induced pneumonitis (RP). METHODS AN...
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