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Article

Functional consequences of ATM sequence variants for chromosomal radiosensitivity.

Genes, chromosomes & cancer - 1 Jun 2004

Gutiérrez-Enríquez Sara, Fernet Marie, Dörk Thilo, Bremer Michael, Lauge Anthony, Stoppa-Lyonnet Dominique, Moullan Norman, Angèle Sandra, Hall Janet

Abstract excerpt

The ATM [for ataxia-telangiectasia (A-T) mutated] protein plays a key role in the detection and cellular response to DNA double-strand breaks. Several single-nucleotide polymorphisms (SNPs) have been described in the ATM gene; however, their association with cancer risk or radiosensitivity remains to be fully established. In this study, the functional consequences of specific ATM SNPs on in vitro...

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Source

Identifiers

PMID: 15101044
DOI: 10.1002/gcc.20025

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Functional consequences of ATM sequence variants for chromosomal radiosensitivity.PMID 15101044Read ↗

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ATM Variants in Breast Cancer: Implications for Breast Radiation Therapy Treatment RecommendationsSemantic proximity Read ↗

Functional variations in the ATM gene and susceptibility to differentiated thyroid carcinoma.Semantic proximity Read ↗

Variants in the ATM gene associated with a reduced risk of contralateral breast cancer.Semantic proximity Read ↗

Functional consequences of sequence alterations in the ATM gene.Semantic proximity Read ↗

Rare variants in the ATM gene and risk of breast cancer.Semantic proximity Read ↗

Functional and computational assessment of missense variants in the ataxia-telangiectasia mutated (ATM) gene: mutations with increased cancer risk.Semantic proximity Read ↗

Risk of cancer by ATM missense mutations in the general population.Semantic proximity Read ↗

Cellular responses to radiation and risk of breast cancer.Semantic proximity Read ↗

Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study.Semantic proximity Read ↗

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