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Article

Accumulation of oxidative stress-related gene polymorphisms and the risk of coronary heart disease events in patients with type 2 diabetes--an 8-year prospective study.

Atherosclerosis - 1 Aug 2014

Katakami Naoto, Kaneto Hideaki, Matsuoka Taka-Aki, Takahara Mitsuyoshi, Osonoi Takeshi, Saitou Miyoko, Kawai Koichi, Ishibashi Fukashi, Kashiwagi Atsunori, Kawamori Ryuzo, Shimomura Iichiro, Yamasaki Yoshimitsu

Abstract excerpt

OBJECTIVE: Oxidative stress, which is provoked in patients with diabetes, plays critical roles in the pathogenesis of coronary heart disease (CHD). We simultaneously determined 5 relatively common genetic variants related to oxidative stress and evaluated the combined effect on CHD. METHODS: We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 years old), determined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24933031
DOI: 10.1016/j.atherosclerosis.2014.05.936

Genes

CYBA
GCLM
MPO
NOS3
SOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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