Article
Polymorphic variations in manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and catalase (CAT) contribute to elevated plasma triglyceride levels in Chinese patients with type 2 diabetes or diabetic cardiovascular disease.
Molecular and cellular biochemistry - 1 Apr 2012
Chen Hong, Yu Ming, Li Ming, Zhao Ruie, Zhu Qihan, Zhou Wenrui, Lu Ming, Lu Yufeng, Zheng Taishan, Jiang Jiamei, Zhao Weijing, Xiang Kunsan, Jia Weiping, Liu Limei
Abstract excerpt
Manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and catalase (CAT) provide the primary antioxidant defense system. Impaired antioxidant defense increases oxidative stress and contributes to the development of type 2 diabetes and diabetic cardiovascular disease (CVD). We preformed a case-control study in Chinese type 2 diabetes patients, to determine if the MnSOD Val16Ala (T→C), GPX1...
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