Article
Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus.
BMC medical genetics - 21 Apr 2008
Flekac Milan, Skrha Jan, Hilgertova Jirina, Lacinova Zdena, Jarolimkova Marcela
Abstract excerpt
BACKGROUND: Reactive oxygen species generated by hyperglycaemia modify structure and function of lipids, proteins and other molecules taking part in chronic vascular changes in diabetes mellitus (DM). Low activity of scavenger enzymes has been observed in patients with DM. Protective role of scavenger enzymes may be deteriorated by oxidative stress. This study was undertaken to investigate the association between...
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