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Article

Combined effect of oxidative stress-related gene polymorphisms on atherosclerosis.

Biochemical and biophysical research communications - 20 Feb 2009

Katakami N, Sakamoto K, Kaneto H, Matsuhisa M, Shimizu I, Ishibashi F, Osonoi T, Kashiwagi A, Kawamori R, Hori M, Yamasaki Y

Abstract excerpt

It is well known that oxidative stress plays critical roles in the pathogenesis of atherosclerosis. In this study, we enrolled 1746 type 2 diabetic subjects, determined 4 common genetic variants related to oxidative stress (glutamate-cysteine ligase modifier subunit (GCLM) C-588T, myeloperoxidase G-463A, human paraoxonase 1 Gln192Arg and NAD(P)H oxidase p22phox C242T polymorphisms), and measured carotid...

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Source

Identifiers

PMID: 19126404
DOI: 10.1016/j.bbrc.2008.12.154

Genes

GCLM

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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