Article
Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with type 1 and type 2 diabetes.
Cardiovascular diabetology - 15 Jan 2015
Mohammedi Kamel, Bellili-Muñoz Naïma, Marklund Stefan L, Driss Fathi, Le Nagard Hervé, Patente Thiago A, Fumeron Frédéric, Roussel Ronan, Hadjadj Samy, Marre Michel, Velho Gilberto
Abstract excerpt
BACKGROUND: Oxidative stress is involved in development of diabetes complications. Extracellular superoxide dismutase (EC-SOD, SOD3) is a major extracellular antioxidant enzyme and is highly expressed in arterial walls. Advanced oxidation protein products (AOPP) and 8-iso-prostaglandin (isoprostane) are markers of oxidative stress. We investigated association of SOD3 gene variants, plasma concentrations of...
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