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Article

Constitutive activity of bitter taste receptors (T2Rs).

Advances in pharmacology (San Diego, Calif.) - 1 Jan 2014

Pydi Sai P, Bhullar Rajinder P, Chelikani Prashen

Abstract excerpt

G protein-coupled receptors (GPCRs) play a vital role in transmitting an extracellular stimuli or signal into an intracellular response in various cells. In some scenarios, GPCRs or their mutants can also signal in the absence of an agonist or an external stimulus, referred to as basal or constitutive activity, and those mutants are termed constitutively active mutants (CAMs). Bitter taste is one of the five...

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PMID: 24931200
DOI: 10.1016/B978-0-12-417197-8.00010-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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