Article
Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Biochemical and biophysical research communications - 31 May 2013
Thalmann Sophie, Behrens Maik, Meyerhof Wolfgang
Abstract excerpt
A complete understanding of bitterness perception requires identification of cognate bitter substances for all human bitter taste receptors (TAS2Rs). However, so far, no agonists have been identified for five of the 25 TAS2Rs, i.e., TAS2R41, TAS2R42, TAS2R45, TAS2R48 and TAS2R60. Due to substanti...
Topics
- Amino Acid Sequence
- Base Sequence
- Chloramphenicol
- Haplotypes
- Humans
- Molecular Sequence Data
- Polymorphism, Single Nucleotide
- Receptors, G-Protein-Coupled
- Structure-Activity Relationship
- Taste
- Taste Buds