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Article

PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study.

Rejuvenation research - 1 Oct 2014

Garatachea Nuria, Fuku Noriyuki, He Zi-Hong, Tian Ye, Arai Yasumichi, Abe Yukiko, Murakami Haruka, Miyachi Motohiko, Yvert Thomas, Venturini Letizia, Santiago Catalina, Santos-Lozano Alejandro, Rodríguez Gabriel, Ricevuti Giovanni, Pareja-Galeano Helios, Sanchis-Gomar Fabian, Emanuele Enzo, Hirose Nobuyoshi, Lucia Alejandro

Abstract excerpt

Focal adhesion is critical for cell survival. The focal adhesion kinase (FAK, or PTK2) is an important component of the human interactome and thus is a potential longevity-related protein. Here we studied the association between two PTK2 gene single-nucleotide polymorphisms (SNPs) (rs7843014, rs7...

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Identifiers

PMID: 24930376
DOI: 10.1089/rej.2014.1570
PMCID: PMC4203112

Genes

PTK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24930376-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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