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Whole-genome sequencing of Chinese centenarians reveals important genetic variants in aging WGS of centenarian for genetic analysis of aging.

Human genomics - 10 Jun 2020

Shen Shuhua, Li Chao, Xiao Luwei, Wang Xiaoming, Lv Hang, Shi Yuan, Li Yixue, Huang Qi

Abstract excerpt

BACKGROUND: Genetic research on longevity has provided important insights into the mechanism of aging and aging-related diseases. Pinpointing import genetic variants associated with aging could provide insights for aging research. METHODS: We performed a whole-genome sequencing in 19 centenarians to establish the genetic basis of human longevity. RESULTS: Using SKAT analysis, we found 41 significantly correlated...

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Identifiers

PMID: 32522283
DOI: 10.1186/s40246-020-00271-7
PMCID: PMC7285530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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