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Article

A functional single nucleotide polymorphism in promoter of ATM is associated with longevity.

Mechanisms of ageing and development - 1 Oct 2010

Chen Tie, Dong Birong, Lu Zhenchan, Tian Baochun, Zhang Jian, Zhou Jianlin, Wu Hongmei, Zhang Yanling, Wu Jinhui, Lin Ping, Zhang Jie, Xu Hong, Mo Xianming

Abstract excerpt

Although the 'ataxia telangiectasia mutated' (ATM) gene plays an important role in physiological processes, such as sensing DNA damage, reducing oxidative stress and protecting telomeres length, little information about ATM and longevity is available. Therefore, we aim to examine the association between genetic variants in promoter of ATM and longevity in Chinese Nonagenarians/Centenarians. Genotyping was...

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Identifiers

PMID: 20816691
DOI: 10.1016/j.mad.2010.08.009

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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