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Article

CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2014

Cleven Arjen H G, Derks Sarah, Draht Muriel X G, Smits Kim M, Melotte Veerle, Van Neste Leander, Tournier Benjamin, Jooste Valerie, Chapusot Caroline, Weijenberg Matty P, Herman James G, de Bruïne Adriaan P, van Engeland Manon

Abstract excerpt

PURPOSE: Data on the prognostic significance of promoter CpG island methylation in colorectal cancer (CRC) are conflicting, possibly due to associations between methylation and other factors affecting survival such as genetic alterations and use of adjuvant therapy. Here, we examine the prognosti...

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Source

Identifiers

PMID: 24928946
DOI: 10.1158/1078-0432.CCR-12-3734

Genes

BRAF
CHFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24928946-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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