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Article

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters.

Nucleic acids research - 1 Jul 2014

Loughery Jayne, Cox Miranda, Smith Linda M, Meek David W

Abstract excerpt

The p53 tumour suppressor is induced by various stress stimuli and coordinates an adaptive gene expression programme leading to growth arrest or cell death. Some stimuli, such as DNA damage, lead to rapid and substantial multisite phosphorylation of p53, nucleated initially through phosphorylatio...

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Identifiers

PMID: 24928858
DOI: 10.1093/nar/gku501
PMCID: PMC4081099

Genes

CDKN1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24928858-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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