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An integrated platform for bovine DNA methylome analysis suitable for small samples

9 Jun 2014

Abstract excerpt

BACKGROUND: Oocytes and early embryos contain minute amounts of DNA, RNA and proteins, making the study of early mammalian development highly challenging. The study of the embryo epigenome, in particular the DNA methylome, has been made accessible thanks to the possibility of amplifying specific sequences according to their initial methylation status. This paper describes a novel platform dedicated to the...

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PMID: 24912542
DOI: 10.1186/1471-2164-15-451

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