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DNA Methylation Patterns Reflect Epigenetic Reprogramming in Bovine Embryos

4 Feb 2010

Abstract excerpt

To understand the epigenetic alterations associated with assisted reproduction technology (ART) and the reprogramming of gene expression that follows somatic cell nuclear transfer (SCNT), we screened a panel of 41 amplicons representing 25 developmentally important genes on 15 different chromosomes (a total of 1079 CpG sites). Methylation analysis was performed on DNA from pools of 80 blastocysts representing...

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PMID: 20132011
DOI: 10.1089/cell.2009.0063

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